The development at the business park, located on the edge of Runcorn, will allow companies to enjoy tax breaks, fast-track planning rules and ultra-fast broadband.
It is one of 11 new enterprise zones to be announced alongside successful bids from the Humber Estuary Renewable Energy Super Cluster; Newquay AeroHub in Cornwall; and MIRA Technology Park in Hinckley, Leicestershire.
Daresbury SIC also joins Airport City in Manchester and Mersey Waters in Liverpool to be afforded enterprise zone status by the Coalition Government.
Prime Minister David Cameron said the zones can become 'trailblazers' for growth, jobs and prosperity across the country. “We are determined to do everything we can to make Britain the best place in the world to start and grow a business,' he said.
'Enterprise zones are a major step towards delivering this; cutting business taxes, easing planning restrictions and giving business the tools they need to invest and expand.'
Business Secretary Vince Cable added: 'Enterprise zones are creating an environment for businesses to grow in places with the most potential. Those the government is announcing today, on top of those already approved, show the range of ambitious plans in place across the country.
'Local Enterprise Partnerships (LEPs) have worked closely with businesses in their communities to put forward a range of high-quality proposals. The successful bids they will now take forward are going to help inject new growth into their economies.'
Daresbury SIC's bid was made by Halton Council and had the backing of both the Liverpool and Greater Manchester LEPs, as well as the local Member of Parliament, Graham Evans.
Speaking at the time of the bid last month, John Downes, Chairman of Daresbury SIC and managing director of joint venture partner Langtree, said the zone would allow the campus to deliver the 'critical infrastructure' and 'accelerate [its] growth strategy significantly'.
'The science and technology sector has shown itself to be very resilient in the face of widespread economic turmoil, meaning our bid represents a low-risk proposition, while the specialist skills and investment required to make this project work ensures minimal displacement of jobs or businesses from elsewhere,' he said.
Graham, who has heavily lobbied for the enterprise zone, commented: “I am absolutely thrilled. A huge amount of hard work and persistent lobbying has paid off. This really is a day to celebrate and I congratulate all those who have helped to secure this decision.
“This enterprise zone, along with the already confirmed Mersey Gateway project, will really help kick-start regeneration in Runcorn New Town and ensure the area is unrivalled as the innovation capital of England.
“This translates into thousands of new hi-tech jobs, massive levels of extra investment and significant economic benefits across Cheshire and the rest of the region. We should be very optimistic about the future of Daresbury.”